KRT17 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : KRT17 antibody; Keratin antibody; type I cytoskeletal 17 antibody; Cytokeratin-17 antibody; CK-17 antibody; Keratin-17 antibody; K17 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Bos taurus (Bovine)
UniProt ID : A1L595
Immunogen : Recombinant Bovine Keratin, type I cytoskeletal 17 protein (1-441AA)
Raised in : Rabbit
Species Reactivity : Bovine
Tested Applications :
Background : Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in partic µLar for the persistence of the anagen (growth) state. Mod µLates the function of TNF-alpha in the specific context of hair cycling. Reg µLates protein synthesis and epithelial cell growth thro µgh binding to the adapter protein SFN and by stim µLating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial \"stem cells\". Acts as a promoter of epithelial proliferation by acting a reg µLator of immune response in skin : promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KRT17
Research Areas : Others