BCL2 (Ab 70) Antibody

Volume : 100 µL
Clone Number :
Aliases : Apoptosis reg µLator Bcl 2 antibody; Apoptosis reg µLator Bcl-2 antibody; Apoptosis reg µLator Bcl2 antibody; AW986256 antibody; B cell CLL/lymphoma 2 antibody; B cell leukemia/lymphoma 2 antibody; Bcl-2 antibody; Bcl2 antibody; BCL2_HUMAN antibody; C430015F12Rik antibody; D630044D05Rik antibody; D830018M01Rik antibody; Leukemia/lymphoma; B-cell; 2 antibody; Oncogene B-cell leukemia 2 antibody; PPP1R50 antibody; Protein phosphatase 1 reg µLatory subunit 50 antibody; Protein phosphatase 1; reg µLatory subunit 50 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P10415
Immunogen : Peptide sequence around aa.68~72 (R-T-S-P-L) derived from Human BCL-2.
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, WB, IHC, IF; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200, IF : 1 : 100-1 : 200
Background : BCL-2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is tho µght to be the cause of follic µLar lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

M µLler IM, et al. (2005) Mol Pharmacol.
Jin Z, Gao F,et al. J Biol Chem 2004 Sep 17; 279(38) : 40209-19.
Kumar Biswas S,et al. Mol Cancer Ther 2004 Mar; 3(3) : 327-34.
Huang ST,et al. (2002)FASEB J; 16(8) : 825-32.
Yamamoto K,et al. (1999) Mol Cell Biol; 19(12) : 8469-78.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BCL2
Research Areas : Cancer;Cell biology;Metabolism;Signal transduction