KCNJ11 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : KCNJ11 antibody; ATP-sensitive inward rectifier potassium channel 11 antibody; IKATP antibody; Inward rectifier K(+) channel Kir6.2 antibody; Potassium channel antibody; inwardly rectifying subfamily J member 11 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14654
Immunogen : Recombinant Human ATP-sensitive inward rectifier potassium channel 11 protein (172-390AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is reg µLated by the concentration of extracell µLar potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracell µLar barium. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and reg µLation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KCNJ11
Research Areas : Neuroscience; Cancer; Cardiovasc µLar; Metabolism; Signal transduction