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ATF2 (Ab 71 or 53) Antibody

https://www.proteomika.com/web/image/product.template/51775/image_1920?unique=2e10e05

Volume : 100 µL
Clone Number :
Aliases : Activating transcription factor 2 antibody; Activating transcription factor 2 splice variant ATF2 var2 antibody; ATF 2 antibody; Atf-2 antibody; Atf2 antibody; ATF2 protein antibody; ATF2_HUMAN antibody; cAMP Response Element Binding Protein 2 antibody; cAMP response element binding protein CRE BP1 antibody; cAMP response element-binding protein CRE-BP1 antibody; cAMP responsive element binding protein 2; formerly antibody; cAMP-dependent transcription factor ATF-2 antibody; cAMP-responsive element-binding protein 2 antibody; CRE BP1 antibody; CRE-BP antibody; CREB 2 antibody; CREB-2 antibody; CREB2 antibody; CREBP1 antibody; Cyclic AMP dependent transcription factor ATF 2 antibody; Cyclic AMP-dependent transcription factor ATF-2 antibody; Cyclic AMP-responsive element-binding protein 2 antibody; D130078H02Rik antibody; D18875 antibody; HB 16 antibody; HB16 antibody; Histone acetyltransferase ATF2 antibody; MGC105211 antibody; MGC105222 antibody; MGC111558 antibody; MGC142504 antibody; mXBP antibody; MXBP protein antibody; Tg(Gzma-Klra1)7Wum antibody; TREB 7 antibody; TREB7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15336
Immunogen : Peptide sequence around aa.69~73 or 51~55 (T-P-T-P-T) derived from Human ATF2.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, WB, IHC, IF; WB : 1 : 500-1 : 1000, IHC : 1 : 50-1 : 200, IF : 1 : 100-1 : 200
Background :
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus : 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cell µLar promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.

Sevilla A, et al. (2004) J Biol Chem. 279(26) : 27458-27465.
Waetzig G H, et al. (2002) J Immunol. 168(10) : 5342-5351.
Abdel-Hafiz H A, et al. (1992) Mol Endocrinol. 6 : 2079-2089.
Gupta S, et al. (1995) Science. 267 : 389-393.
Van Dam H, et al. (1995) EMBO J. 14(8) : 1798-1811.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATF2
Research Areas : Epigenetics and Nuclear Signaling;Immunology

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