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Desmin (Muscle Cell Marker) (DES/1711) , CF640R conjugate , 0.1mg / mL

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Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helicalcoiled-coil molecules arranged on an imperfect helical lattice , and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin , a related class III IF , are both expressed during skeletal muscle development. Desmin , a 469 amino acid protein found near the Z line in sarcomeres , is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth , skeletal , and cardiac muscles. The antibody reacts with leiomyomas , leiomyosarcoma , rhabdomyomas , rhabdomyosarcoma , and perivascular cells of glomus tumors of the skin._x000D_ _x000D_ Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_

192,00 € 192.0 EUR 192,00 €

192,00 €

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Garantie satisfait ou remboursé de 30 jours
Expédition : 2-3 jours ouvrables