Clathrin , Heavy Chain(CHC/1432) , CF488A conjugate , 0.1mg / mL

Recognizes protein of 192 kDa , which is identified as Clathrin Heavy Chain. Clathrin is composed of three heavy chains and three light chains , which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain , a distal segment and a proximal segment containing a light chain-binding site. The proximal segment of the Clathrin HC protein is essential for interactions between Clathrin heavy chains and light chains , which result in the formation of the triskelion structure. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.