Cytokeratin 18 (KRT18) (KRT18/2808R) , CF594 conjugate , 0.1mg / mL

This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract , lung , breast , pancreas , ovary , and thyroid. Cytokeratin 18 , which belongs to the type A (acidic) subfamily of low molecular weight keratins , exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract , respiratory tract and urogenital tract , as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18._x000D_ _x000D_ Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_