Cytokeratin , pan (Epithelial Marker)(PCK/3150) , CF594 conjugate , 0.1mg / mL

Anti-cytokeratin clone PCK/3150 demonstrates a broad spectrum of cytokeratin reactivity. In normal tissues , PCK/3150 is reactive with most epithelial types , including bile ducts and hepatocytes in liver , bladder epithelium , breast ducts , bronchial epithelium , endometrium , intestinal epithelium of stomach , duodenum , ileum , colon , rectum , pancreas , ovarian epithelium , pancreatic acini , pituitary acini , pneumocytes , prostate , thyroid , skin (positive on the basal layer and negative on the superficial layers of squamous epithelium) , and apocrine and sweat glands. In tumors , PCK/3150 is reactive with most carcinomas , including breast , transitional cell (TCC) , renal cell (RCC) , lung adenocarcinoma , lung small cell , lung squamous cell , endometrial , prostate , ovarian , hepatocellular (HCC) , colorectal CA , stomach and thyroid. It is negative in certain normal tissues , including brain , lymphocytes and all cells of hematolymphoid origin , muscle , brain , nerves , endothelium and in certain tumors including most melanomas , sarcomas , lymphomas , primitive neuroectodermal tumors (PNET)/Ewings and gastrointestinal stromal tumors (GIST). Positivity has been seen on some dendritic cells in lymph nodes , some endothelia , and some muscle cells. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.