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PAX2 (Renal Cell & Ovarian Carcinoma Marker) (PAX2/1104) , Biotin conjugate , 0.1mg / mL

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This antibody recognizes a protein of 42 kDa , which is identified as PAX2. It is a member of the paired box family of transcription factors , which is required for development and proliferation of the kidney , brain , and Müllerian organs. PAX2 genes contain a highly conserved DNA sequence within the paired box region , which encodes a DNA-binding domain , enabling PAX proteins to bind the promoters of specific genes to transcriptionally regulate their expression. PAX2 is specifically expressed in the developing central nervous system , eye , ear , and urogenital tract , and is essential for the development of these organs. In normal adult tissues PAX2 was mainly detected in the urogenital system , including kidney , ureteric epithelium , fallopian tube epithelium , ovary and uterus. In tumors , PAX2 has been detected in renal cell carcinomas , Wilms' tumors , nephrogenic adenomas and papillary serous carcinoma of the ovary. PAX2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry._x000D_ _x000D_ Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_

192,00 € 192.0 EUR 192,00 €

192,00 €

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Garantie satisfait ou remboursé de 30 jours
Expédition : 2-3 jours ouvrables