PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)(PMEPA1/2698) , Biotin conjugate , 0.1mg / mL

PMEPA1 (prostate transmembrane protein , androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate , kidney and ovary , PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels , specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors , suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer._x000D_ _x000D_ Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_