C5AR1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : ANAPHYLATOXIN RECEPTOR antibody; C5a anaphylatoxin chemotactic receptor antibody; C5a anaphylatoxin receptor antibody; C5A antibody; C5a ligand antibody; C5a-R antibody; C5aR antibody; C5AR_HUMAN antibody; c5ar1 antibody; C5R1 antibody; CD88 antibody; CD88 antigen antibody; Complement component 5 receptor 1 antibody; Complement component 5 receptor 2 antibody; Complement component 5a receptor 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P21730
Immunogen : Recombinant Human C5a anaphylatoxin chemotactic receptor 1 protein (1-36AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed : 1847994, PubMed : 8182049, PubMed : 7622471 PubMed : 9553099, PubMed : 10636859, PubMed : 15153520). The ligand interacts with at least two sites on the receptor : a high-affinity site on the extracell µLar N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed : 8182049, PubMed : 7622471 PubMed : 9553099). Receptor activation stim µLates chemotaxis, gran µLe enzyme release, intracell µLar calcium release and superoxide anion production (PubMed : 10636859, PubMed : 15153520).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C5AR1
Research Areas : Cancer; Immunology; Metabolism; Signal transduction