DSCAM Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : CHD2 42 antibody; CHD2 52 antibody; CHD2 antibody; Down syndrome cell adhesion molec µLe antibody; DSCAM antibody; DSCAM_HUMAN antibody; human CHD2-52 down syndrome cell adhesion molec µLe 2; 9 antibody; OTTHUMP00000109193 2 antibody; SD11109p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60469
Immunogen : Recombinant Human Down syndrome cell adhesion molec µLe protein (1711-1867AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cell adhesion molec µLe that plays a role in neuronal self-avoidance. Promotes rep µLsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (PubMed : 10925149). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding (PubMed : 18585357, PubMed : 19196994). Enhances netrin-induced phosphorylation of PAK1 and FYN (PubMed : 15169762). Mediates intracell µLar signaling by stim µLating the activation of MAPK8 and MAP kinase p38 (PubMed : 18585357, PubMed : 19196994). Adhesion molec µLe that promotes lamina-specific synaptic connections in the retina : expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DSCAM
Research Areas : Neuroscience