LGMN Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : AEP antibody; Asparaginyl endopeptidase antibody; cysteine 1 antibody; Cysteine protease 1 antibody; EC 3.4.22.34 antibody; Legumain antibody; LGMN antibody; LGMN_HUMAN antibody; LGMN1 antibody; Protease antibody; Protease cysteine 1 (legumain) antibody; Protease cysteine 1 antibody; PRSC1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99538
Immunogen : Recombinant Human Legumain protein (199-312AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tub µLes. Required for normal degradation of internalized EGFR. Plays a role in the reg µLation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LGMN
Research Areas : Cancer; Cell biology; Immunology; Metabolism; Signal transduction