DAD1 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : DAD 1 antibody; DAD-1 antibody; dad1 antibody; DAD1_HUMAN antibody; Defender against cell death 1 antibody; Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1 antibody; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antibody; Oligosaccharyl transferase subunit DAD1 antibody; OST 2 antibody; OST2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P61803
Immunogen : Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 protein (1-113AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed : 22467853). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic retic µLum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes. Loss of the DAD1 protein triggers apoptosis (PubMed : 22467853).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DAD1
Research Areas : Cell biology