DKK2 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : Dickkopf 2 antibody; Dickkopf gene 2 antibody; Dickkopf homolog 2 antibody; Dickkopf related protein 2 antibody; Dickkopf WNT signaling pathway inhibitor 2 antibody; Dickkopf-2 antibody; Dickkopf-related protein 2 antibody; Dickkopf2 antibody; DKK 2 antibody; Dkk-2 antibody; Dkk2 antibody; DKK2_HUMAN antibody; hDkk 2 antibody; hDkk-2 antibody; hDkk2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UBU2
Immunogen : Recombinant Human Dickkopf-related protein 2 protein (34-259AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt reg µLated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the ad µLt, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DKK2
Research Areas : Stem cells