Disintegrin EC3B Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : Disintegrin EC3B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Echis carinatus
UniProt ID : P81631
Immunogen : Recombinant Echis carinatus Disintegrin EC3B protein (1-67AA)
Raised in : Rabbit
Species Reactivity : Echis carinatus
Tested Applications : ELISA
Background : Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vasc µLar cell adhesion molec µLe 1 (VCAM-1) and mucosal addressin cell adhesion molec µLe 1 (MADCAM-1). It is also a weaker inhibitor of alpha-5/beta-1 (ITGA5/ITGB1) and alpha-2b/beta-3 (ITGA2B/ITGB3) integrins. The inhibitory activity of EC3 towards alpha-4 integrins is associated with the MLD sequence of EC3B subunit. The ability of EC3 to inhibit ITGA5/ITGB1 resides in both subunits A and B.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others