gH Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : gH antibody; µL75 antibody; Envelope glycoprotein H antibody; gH antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human) cytomegalovirus
UniProt ID : P12824
Immunogen : Recombinant Human cytomegalovirus Envelope glycoprotein H protein (24-195AA)
Raised in : Rabbit
Species Reactivity : Human cytomegalovirus
Tested Applications : ELISA
Background : The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis (By similarity). In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA. The gH-gL- µL128- µL130- µL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : gH
Research Areas : Others