DNAJC10 Antibody Biotin conjugated

Volume : 50 µL
Clone Number :
Aliases : DNAJC10 antibody; ERDJ5 antibody; UNQ495/PRO1012DnaJ homolog subfamily C member 10 antibody; EC 1.8.4.- antibody; Endoplasmic retic µLum DNA J domain-containing protein 5 antibody; ER-resident protein ERdj5 antibody; ERdj5 antibody; Macrothioredoxin antibody; MTHr antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IXB1
Immunogen : Recombinant Human DnaJ homolog subfamily C member 10 protein (521-793AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Endoplasmic retic µLum dis µLfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic retic µLum by catalyzing the removal of non-native dis µLfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic retic µLum-associated degradation (ERAD) by reducing incorrect dis µLfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the dis µLfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic retic µLum stress.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNAJC10
Research Areas : Signal transduction