ARRDC3 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : ARRDC3 antibody; KIAA1376 antibody; Arrestin domain-containing protein 3 antibody; TBP-2-like inducible membrane protein antibody; TLIMP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96B67
Immunogen : Recombinant Human Arrestin domain-containing protein 3 protein (1-270AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Adapter protein that plays a role in reg µLating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed : 20559325, PubMed : 21982743, PubMed : 23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed : 20559325, PubMed : 23208550). May recruit NEDD4 to ADRB2 (PubMed : 20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed : 23208550).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ARRDC3
Research Areas : Cell biology