DKK3 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : Dickkopf 3 antibody; Dickkopf 3 homolog (Xenopus laevis) antibody; Dickkopf 3 homolog antibody; Dickkopf homolog 3 antibody; Dickkopf related protein 3 antibody; Dickkopf related protein 3 Precursor antibody; Dickkopf WNT signaling pathway inhibitor 3 antibody; Dickkopf; Xenopus; homolog of; 3 antibody; Dickkopf-3 antibody; Dickkopf-related protein 3 antibody; Dickkopf3 antibody; DKK 3 antibody; Dkk-3 antibody; DKK3 antibody; DKK3_HUMAN antibody; hDkk 3 antibody; hDkk-3 antibody; hDkk3 antibody; Reg µLated in glioma antibody; REIC antibody; RIG antibody; RIG-like 5-6 antibody; RIG-like 7-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UBP4
Immunogen : Recombinant Human Dickkopf-related protein 3 protein (22-350AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt reg µLated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the ad µLt, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DKK3
Research Areas : Signal transduction; Stem cells