DAB1 (Ab 232) Antibody

Volume : 100 µL
Clone Number :
Aliases : Dab 1 antibody; Dab reelin signal transducer 1 antibody; Dab; reelin signal transducer; homolog 1 (Drosophila) antibody; Dab1 antibody; DAB1_HUMAN antibody; Disabled homolog 1 antibody; Disabled homolog 1 Drosophila antibody; Scm antibody; Scr antibody; Scrambler antibody; Yot antibody; Yotari antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75553
Immunogen : Peptide sequence around aa.230~234 (G-V-Y-D-V) derived from Human Dab1.
Raised in : Rabbit
Species Reactivity : Human, Mouse, Rat
Tested Applications : ELISA, IHC; IHC : 1 : 50-1 : 100
Background : The laminar organization of m µLtiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1 and the protein encoded by this gene is tho µght to be a signal transducer that interacts with protein kinase pathways to reg µLate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their f µLl length nature has not been determined.

Kelian Chen, et,al. (2003) J. Cell Sci ; 117 : 4527 - 4536.
Vera Strasser, et,al. (2004) Mol. Cell. Biol ; 24 : 1378 - 1386.
Izhar Ben-Shlomo, et,al. (2003) Sci. STKE ; 2003 : 9.
H. M. Kim, et,al. (2002) PNAS ; 99 : 4020.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conj µgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conj µgate : Non-conj µgated
Buffer : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form : liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DAB1
Research Areas : Neuroscience;Signal transduction