Amphiphysin antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Amphiphysin(AMPH), a synaptic vesicle-associated protein that is highly concentrated in nerve terminal, is an autoantigen of Stiff-Man syndrome with breast cancer. Amphiphysin contains a N-terminal BAR(Bin1/Amphiphysin/Rv167) domain followed by an endocytosis domain, and a C-terminal SH3 domain. Amphiphysin has been proposed to function as a linker between the clathrin coat and dynamin in the endocytosis of synaptic vesicles. It may also participate in mechanisms of reg µLated exocytosis in synapses and certain endocrine cell types.
Immunogen : amphiphysin
Aliases : Amphiphysin,AMPH1AMPH
Observed MW : 120 kDa
Uniprot ID : P49418
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IP
Recommended dilution : WB : 1 : 500-1 : 5000; IHC : 1 : 20-1 : 200; IP : 1 : 500-1 : 5000
Gene ID :
Research Area : Neuroscience