AMPK gamma2 antibody

The AMPK γ2 (gamma 2) antibody is a highly specific immunoreagent designed to detect the gamma 2 regulatory subunit of AMP-activated protein kinase (AMPK), a central metabolic regulator. The γ2 subunit, encoded by the PRKAG2 gene, is one of the three isoforms that modulate AMPK activity in response to changes in intracellular AMP/ATP and ADP/ATP ratios.

This antibody is typically generated using a peptide or recombinant fragment corresponding to the C-terminal or unique regions of the γ2 isoform, ensuring isoform specificity and minimal cross-reactivity with γ1 or γ3 subunits. It is validated for use in Western blotting, immunoprecipitation, and immunohistochemistry, depending on the clone and host species.