Cytokeratin 1 specific antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin-1 is type II keratin. It is a specific marker for terminal differentiation in mammalian epidermis. It is specifically expressed in the spinous and gran µLar layers of the epidermis with family member KRT10 and mutations in these genes have been associated with b µLlous congenital ichthyosiform erythroderma. This antibody is specifically against ketatin I.
Immunogen : keratin 1
Aliases : 67 kDa cytokeratin, CK 1 CK1 Cytokeratin 1 keratin 1 KRT1
Observed MW : 67 kDa
Uniprot ID : P04264
Reactivity : Human, Mouse
Application : ELISA, IP, IF, WB, IHC
Recommended dilution : WB : 1 : 500-1 : 5000; IP : 1 : 200-1 : 2000; IHC : 1 : 20-1 : 200; IF : 1 : 20-1 : 200
Gene ID :
Research Area : Immunology, Developmental biology