DHDDS antibody
Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : With DHDDS, forms the dehydrodolichyl diphosphate synthase(DDS) complex, an essential component of the dolichol monophosphate(Dol-P) biosynthetic machinery. Adds m µLtiple copies of isopentenyl pyrophosphate(IPP) to farnesyl pyrophosphate(FPP) to produce dehydrodolichyl diphosphate(Dedol-PP), a precusrosor of dolichol which is utilized as a s µgar carrier in protein glycosylation in the endoplasmic retic µLum(ER). Reg µLates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.
Immunogen : dehydrodolichyl diphosphate synthase
Aliases : HDS
Observed MW : 34 kDa
Uniprot ID : Q86SQ9
Reactivity : Human, Mouse, Rat
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID : 79947
Research Area : Metabolism