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IDO1 antibody

https://antibody.odoo.com/web/image/product.template/91363/image_1920?unique=cd1bae2

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway(PubMed : 17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that wo µLd res µLt from uncontrolled and overreacting immune responses(PubMed : 25691885). Tryptophan shortage inhibits T lymphocytes division and accum µLation of tryptophan catabolites induces T-cell apoptosis and differentiation of reg µLatory T-cells(PubMed : 25691885). Acts as a suppressor of anti-tumor immunity(PubMed : 23103127, PubMed : 25157255, PubMed : 14502282, PubMed : 25691885). Limits the growth of intracell µLar pathogens by depriving tryptophan(PubMed : 25691885). Protects the fetus from maternal immune rejection(PubMed : 25691885).
Immunogen : indoleamine 2,3-dioxygenase 1
Aliases : CD107B, IDO, IDO 1 IDO1 INDO, indoleamine 2,3 dioxygenase 1
Observed MW : 42 kDa
Uniprot ID : P14902
Reactivity : Human, Mouse, Rat
Application : ELISA, IHC, WB
Recommended dilution : WB : 1 : 1000-1 : 4000; IHC : 1 : 50-1 : 500
Gene ID : 3620
Research Area : Cancer, Metabolism

353,10 € 353.1 EUR 353,10 €

353,10 €

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Conditions générales
Garantie satisfait ou remboursé de 30 jours
Expédition : 2-3 jours ouvrables