LILRB4 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background : This gene is a member of the leukocyte immunoglob µLin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracell µLar immunoglob µLin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molec µLes on antigen-presenting cells and transduces a negative signal that inhibits stim µLation of an immune response. The receptor can also function in antigen capture and presentation. It is tho µght to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. M µLtiple transcript variants encoding different isoforms have been found for this gene.
Immunogen : Leukocyte immunoglob µLin-like receptor subfamily B member 4
Aliases : LILRB4, CD85K, ILT-3, ILT3, LIR-5, LIR5
Observed MW : 49 kDa
Uniprot ID : Q8NHJ6
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IF
Recommended dilution : WB : 1 : 500-1 : 2000; IHC : 1 : 50-1 : 200; IF : 1 : 50-1 : 200
Gene ID :
Research Area :